Agent X

After her inauguration, newly elected Vice President Natalie Maccabee is initiated into a covert world of danger by her chief steward, Malcolm Millar and Chief Justice Caleb Thorne. Contrary to what the public believes, the job of Vice President is far from ceremonial. In fact, enshrined in a secret version of the Constitution is a section endowing Natalie with her own secret agent, John Case, to be deployed in times of crisis. Natalie quickly finds herself in play when the daughter of FBI Director Stanton is kidnapped, and authorities are helpless in rescuing her.

One of John's old nemeses, terrorist Malik Ahmad, steals an arsenal of nuclear warheads and a scientist to activate them. John is forced to work with his enemy Olga Petrovka in order to destroy them and rescue the scientist. Meanwhile, Natalie and Malcolm endeavor to protect John's identity from an FBI investigation.

John breaks the protocol of the Agent X Brotherhood to protect his former lover, Pamela Richardson, from members of a Washington D.C. based cabal intent on taking down the President. Meanwhile, Natalie, Malcolm and Judge Thorne work to unmask the members of the conspiracy.

The cabal trail leads John to a lawless Mexican town, where he is drawn into a deadly feud between the local drug lord, nicknamed El Diablo, and the town's police chief, Luna. At the same time, Natalie probes into a romantic connection between her late husband, Steven, and the fiancé of her political adversary, Speaker of the House Miles Latham.

A biological weapon is used in a failed assassination attempt on a high ranking government official. John, Natalie, and Malcolm investigate the case, and quickly find themselves racing the clock to stop a domestic terrorist group from deploying the virus on a greater, catastrophic scale.

John poses as a Secret Service agent and accompanies Natalie on a covert peace-talk mission. Before long, their helicopter is shot down and they're left stranded in the middle of nowhere, with very dangerous people on the hunt for them.

John is imprisoned in a basement by an unexpected captor, and Malcolm desperately sets out to rescue him.

A disguised John infiltrates a party on a reclusive billionaire's island in a mission to steal a high-tech weapon. Meanwhile, Natalie tries to contain fallout from a conspiracy.

John is blackmailed by a terrorist into going on a suicide mission, employing the Geryon to accomplish the catastrophic deed.

John must rescue Natalie, Eckhart and a delegation of international leaders from a hostage crisis in the Paris Opera house.