Paul O'Grady's Little Heroes

In the first episode of series, Paul meets five-year-old Daniel who has been in the hospital for a month unable to walk properly after banging his knee whilst playing at home. Just after his accident, Daniel began struggling to walk and he was diagnosed with a rare type of arthritis.

In the second episode Paul meets 13-year-old Lola who has been in hospital for four weeks after being diagnosed with Juvenile Dermatomyositis which has caused inflammation of her muscles and skin. When Paul meets Lola her muscles are so weak and she can't walk, but her mum explains that just six weeks earlier she had been fine. The condition affects one in a million people and Lola needs physiotherapy to help her. Paul is there when Lola tried to take some steps for the first time in two months.

Also in the programme, Paul meets ten-year-old Oscar who has Tourette's. Oscar mostly has motor ticks, which means he sniffs and coughs. He explains that it's a human glitch which causes him to have involuntary movements. But he tells Paul that after developing Tourette's he became too anxious to leave the house.

Paul hears the story of six-year-old Noah, who was born with a genetic disorder that affects the body's organs and has been referred to Great Ormond Street for the removal of his kidney, which stopped working a long time ago. The presenter also meets a couple of two-year-olds - Lucas who has a detached retina and needs laser surgery on his eye and Taylor-Rose who has accidentally swallowed a watch battery.

In episode four Paul meets five-year-old Cora who has Cerebral Palsy. Thirty thousand children in the UK have the condition which affects coordination and muscle control. Cora's mum Poonam explains that Cora has a stiffness in the right side of her body which is causing her to limp and struggle with normal movements.

Cora is at GOSH to take part in ground breaking research which uses Botox to relax the over-active muscles. Paul goes with Cora to the sensory room to try to distract and relax her whilst she has the injections. And the programme follows Cora after the injections to see if they have worked.

Also in episode four, Paul reveals that he's developed a soft-spot for babies. GOSH treats 6000 babies every year and Paul goes to meet three-month-old Oliver who was born with a cleft lip. Paul is with Oliver as he enters theatre to have his cleft lip repaired.

In episode five Paul meets 13-year-old Noah who is at GOSH to have an operation on his skull because part of it is pressing on his spinal cord. Noah's mum Georgina tells the programme that Noah is anxious about the surgery after undergoing emergency surgery on his brain when he was just six.

Paul meets charming four-year-old Lucy, who has travelled down from Glasgow for the latest check-up to monitor her pulmonary hypertension - a high blood pressure condition that affects the lungs. He also meets remarkable 13-year-old Connor, who is on the isolation ward as he prepares for a bone marrow transplant to help treat leukaemia. As Connor needs to live in a totally sterile environment to protect his weakened immune system, Paul can only speak to him through a window - but that doesn't stop him finding a number of fun and interesting ways to keep Connor occupied during his recovery.