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Twisted Sisters takes viewers inside the most shocking crimes ever committed by the unlikeliest of pairs. Sometimes these sisters work together to commit a crime, but often the duo can turn against one another with the deadliest of outcomes. The series interviews immediate family members and close friends to learn what triggered the sisters' path towards a life of crime. Investigators and law enforcement anchor each story as they recount firsthand their unraveling of the case and try to make sense of the crimes committed.
The four Gilbert sisters struggle through a tough childhood made worse when it's suspected that Shannan, the oldest sister, has become a victim of the Long Island Serial Killer. Her mother and sisters embark on a fight for justice for the slain Shannan as Sarra begins a tragic decline into schizophrenia. When Shannan's body is finally found, Sarra's delusions worsen, leaving the question: will both sisters be lost?
Georgia and Jeannie Plummer are two of ten siblings. They remain close until Georgia absconds with much of their inheritance from their mother, Birdie. The sisters don't speak for three years until Georgia once again reaches out to Jeannie for help. Being a good sister, Jeannie can't resist. But soon, Jeannie falls sick, and questions begin to arise.
Denice and Aaron Smith appear to be the perfect, loving couple until Denice's infidelity crumbles the marriage. The divorce proceedings are bitter, and Aaron is awarded custody of the children. Not long after, Aaron is found dead in what appears to be a robbery gone wrong. The kids are missing, as is Denice. After a massive manhunt, investigators find the kids safe and sound, with Denice. But there is more to the story than meets the eye.
A serious childhood illness limits the mental development of Debbie Burns, requiring her older sister Barbara to care for her. For nearly forty years, the sisters live a modest, peaceful life together in St. Petersburg, Florida. But a substantial inheritance disturbs the calm in the Burns home, pitting one sister against the other until, finally, one of them snaps.
Sisters Janice and Betty move from Hope, IN to Seadrift, TX looking for a clean start. But trouble follows them to the Texas coast as Janice's marriage soon falls apart. Resentment and anger build until finally, the sisters plot a murder. However, the plan has a fatal flaw, as they leave their victim lying by the side of the road, leading to an intense cover-up and cataclysmic chase the sisters never saw coming.
Two sisters, with little in common, cope with their overly protective mother in very different ways and with very deadly consequences.
A family's search for new beginnings backfires when their move from Hawaii to Alaska creates an environment perfect for murder.
A bitter sibling rivalry takes a dark turn when one sister recruits a local gang to take part in a deadly game of pay back.
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